Bisquick Cheeseburger Pie

Bisquick Cheeseburger Pie stands the test of time for good reason. It fuses the familiar flavors of a cheeseburger into a cozy, sliceable casserole. With simple steps, fresh ingredients, and endless possibilities for tweaking, it’s an approachable weeknight staple that doubles as a nostalgic weekend treat. Here, I’ll walk you through everything you need to know to master this beloved dish, from the essentials of the filling to clever variations, helpful tricks, and serving suggestions.

What is Bisquick Cheeseburger Pie?

At its core, Bisquick Cheeseburger Pie brings together seasoned ground beef, onions, eggs, milk, Bisquick baking mix, and cheese. The Bisquick settles as a tender, golden crust, while the savory filling holds all the classic cheeseburger flavors. No need to fuss with pastry from scratch—a big reason for its lasting popularity.

Key Ingredients and Their Roles

Ground Beef: Go for 80-85% lean ground beef for the right balance between flavor and texture. Leaner beef can make the pie dry; fattier blends may turn greasy.
Onion: Yellow or white onions add sweet savoriness as they cook. Dice them small so every bite melds into the filling.
Cheddar Cheese: Sharp sliced from a block melts smoothly and brings richness. You can use mild cheddar or try Monterey Jack for variety.
Bisquick Baking Mix: This blend of flour, leavening agents, and shortening forms the iconic crust. It’s the shortcut that makes the “impossible pie” possible.
Eggs and Milk: These bind the mixture and set as it bakes, holding the crust together and giving the pie structure.
Salt and Basic Seasonings: Salt brings it all together, while a dash of black pepper or garlic powder can add depth.

Optional Add-ins and Customizations

Vegetables: Chopped bell pepper, mushrooms, or frozen peas work great for extra texture and nutrition.
Condiments: A tablespoon of ketchup, mustard, or relish stirred into the beef layer captures true cheeseburger flavor.
Alternative Proteins: Try ground turkey or chicken for a leaner option, or a plant-based beef substitute for a vegetarian twist.

Essential Tools and Setup

A 9-inch glass or ceramic pie dish (deep-dish works, but adjust baking time accordingly).
A sturdy skillet for browning the beef and onions.
Mixing bowls, spatula, whisk, and a cheese grater.

Lightly grease the pie dish before assembling to prevent sticking and allow for easy serving.

Step-by-Step Recipe: Bisquick Cheeseburger Pie

Ingredients

Ingredient	Amount
Ground beef	1 lb (80-85% lean)
Onion, diced	1 medium
Salt	½ tsp
Cheddar cheese, shredded	1 cup (about 4 oz)
Bisquick baking mix	½ cup
Milk	1 cup
Eggs	2 large
Black pepper, garlic powder (optional)	To taste

Instructions

Preheat the oven to 400°F (200°C). Grease the pie dish with butter or nonstick spray.
Brown the beef and onion. In a large skillet, combine ground beef and diced onion. Cook over medium heat until beef is no longer pink—about 8 minutes. Drain off any excess fat, then stir in salt (and pepper, if using).
Assemble the filling. Spread the beef mixture evenly in the bottom of the pie dish. Sprinkle shredded cheddar cheese on top of the meat.
Mix Bisquick topping. In a bowl, whisk together Bisquick, milk, and eggs until smooth. Pour this batter gently over the beef and cheese layers.
Bake. Place in the oven for 25 minutes. The pie is ready when the top is set and lightly golden, and a knife inserted in the center comes out clean.
Rest, slice, and serve. Allow the pie to cool for 5-10 minutes before slicing. This helps it hold together and makes serving easier.

Tips for Perfect Cheeseburger Pie

Sauté the Onion Thoroughly: This step ensures sweetness and removes any raw taste.
Grate Your Own Cheese: Pre-shredded cheese often contains anti-caking agents, affecting melt and flavor.
Let the Pie Rest: Resting makes for cleaner slices and easier serving.
Customize Crust Texture: For a slightly crispier top, broil the baked pie for 2 minutes at the end, watching closely.
Make Ahead: You can assemble the pie a day in advance and refrigerate it unbaked. When ready, plan to add 5–7 extra minutes to the baking time.

Creative Variations to Try

Bacon Cheeseburger Pie: Add ½ cup cooked bacon crumbles to the beef mixture for a smoky twist.
Southwest Style: Mix 1 tablespoon taco seasoning into the beef. Top with chopped tomatoes and serve with salsa and sour cream.
Italian-Inspired: Use mozzarella cheese instead of cheddar, stir in 1 teaspoon Italian seasoning, and drizzle with marinara sauce before serving.
Vegetable Lovers: Add ½ cup chopped mushrooms, zucchini, or bell peppers for extra flavor and nutrition.
Gluten-Free Option: Use gluten-free Bisquick or a homemade gluten-free baking mix.

Serving Suggestions

Pair Bisquick Cheeseburger Pie with simple, fresh sides for a well-rounded meal. Try:

Crisp green salad: Romaine, arugula, or spinach tossed with a vinaigrette.
Roasted vegetables: Brussels sprouts, carrots, or green beans work well.
Potato sides: Oven fries, potato wedges, or even hash browns for a brunch version.
Fruit salad: Adds a cool, sweet contrast—especially good when serving kids.

A classic dill pickle spear and a swirl of ketchup or mustard bring the cheeseburger vibes home. You might also enjoy topping your slice with a spoonful of salsa or a scoop of guacamole for a new twist.

Storage and Freezing

Leftover Pie: Cool slices, wrap tightly, and store in the refrigerator for up to 4 days. Reheat in the oven at 350°F for 10-12 minutes for the best texture.
Freezing: Bisquick Cheeseburger Pie freezes well. Cool completely, wrap tightly, and freeze for up to 3 months. Thaw in the fridge overnight, then bake at 350°F until warmed through and the crust is crisp.

Making Your Own Bisquick Mix

If you find your pantry without a box of Bisquick, homemade baking mix works perfectly. For every ½ cup needed for the recipe, combine:

½ cup all-purpose flour
1 teaspoon baking powder
½ teaspoon salt
1 tablespoon cold butter (cut in until the mix resembles fine crumbs)

Store any leftover mix in the fridge in an airtight container for up to two weeks.

Frequently Asked Questions

Can I double the recipe? Yes. Use a 9×13-inch baking dish, double all ingredients, and increase bake time to 30-35 minutes.
What if I don’t have a pie dish? A square glass baking dish or cast iron skillet will work in a pinch; just watch the thickness and adjust cooking time.
Can I make this dairy-free? Use your favorite non-dairy milk and a vegan cheese alternative.
Why is my pie runny? Too much fat from the beef or extra liquid from veggies can cause this. Drain beef well and sauté veggies before adding.

Bisquick Cheeseburger Pie will always have a place at the family table. Its blend of quick prep, familiar flavors, and adaptability make it a smart choice for both beginners and seasoned cooks. Whether you stick with the classic or try a new variation, you get a comforting, satisfying main dish that fits every season and appetite. Try tweaking the fillings or toppings to make it your own, then dig in and enjoy the comfort in every bite.